Antimycin A3

Antimycin A3

$255.00 - 1 mg

$894.00 - 5 mg

All prices in Australian dollars

Code
BIA-A1444
Synonyms
Blastmycin, NSC 58239
CAS #
522-70-3
Molecular Formula
C26H36N2O9
Molecular Weight
520.6
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Clear

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Application Notes

Antimycin A3 is a homologue of the antimycin complex, first isolated in 1958 from Streptomyces blastimyceticus and co-produced with antimycin A4. Antimycin A3 is a more polar analogue of A1 and A2. Like all antimycins, antimycin A3 is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active. Lack of availability of the individual antimycin components has hindered greater understanding of the common and unique molecular targets of the components of the antimycin complex.

References

  • Studies on the chemical structure of blastmycin. Yonehara H. & Takeuchi S. J. Antibiotics Ser. A 1958, 11, 254.

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