Lydicamycin

Lydicamycin

$365.00 - 0.50 mg

$1,280.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-L1047
CAS #
133352-27-9
Molecular Formula
C47H74N4O10
Molecular Weight
855.1
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.

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Application Notes

Lydicamycin belongs to a novel structural class with highly selective antibiotic activity. Recent research has shown that lydicamycin and the related metabolites, TPU-0037A and TPU-0037C, are highly active against MRSA. Lydicamycin is also closely related to BN 4515N which was isolated from a strain of Microtetraspora as a neuritogenic agent.

References

  • TPU-0037-A, B, C and D, novel lydicamycin congeners with anti-MRSA activity from Streptomyces platensis TP-A0598. Furumai T. et al., J. Antibiot. 2002, 55, 873.
  • A new neuritogenetic compound BU-4514N produced by Microtetraspora sp. Toda S. et al., J Antibiot. 1993, 46, 875.
  • Lydicamycin, a new antibiotic of a novel skeletal type. I. Taxonomy, fermentation, isolation and biological activity. Hayakawa Y. et al., J Antibiot. 1991, 44, 282.

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