Leucanicidin

Leucanicidin

$280.00 - 0.50 mg

$980.00 - 2.50 mg

All prices in Australian dollars

Code
BIA-L1369
CAS #
91021-66-8
Molecular Formula
C42H70O13
Molecular Weight
783
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. NOTE: forms methyl ketal on long term storage in methanol.

Download Data Sheets

Product Data Sheet

Application Notes

Leucanicidin is a potent nematocide and insecticide belonging to the bafilomycin class. Lack of access to the pure metabolite has limited its investigation, however structural differences between leucanicidin and the bafilomycins offer scope for investigations into the use of V-ATPases as therapeutic targets.

References

  • The structure of leucanicidin, a novel insecticidal macrolide produced by Streptomyces halstedii. Isogai A. et al., Agric. Biol. Chem. 1984, 48, 1379.
  • Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis. Xu J. et al., Histol. Histopathol. 2007, 22, 443.

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