Demethoxyviridiol

Demethoxyviridiol

$285.00 - 1 mg

$1,000.00 - 5 mg

All prices in Australian dollars

Code
BIA-D1025
CAS #
56617-66-4
Molecular Formula
C19H16O5
Molecular Weight
324.3
Purity
>95% by HPLC
Long Term Storage
-20°C
Solubility
Soluble in ethanol, methanol, DMF or DMSO. NOTE: stability problems if stored in methanol for protracted periods.

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Application Notes

Demethoxyviridiol is a fungal metabolite belonging to the wortmannin and viridin classes. An inhibitor of phosphatidylinositol 3-kinase, demethoxyviridiol affects phospholipid signalling and proliferation of Swiss 3T3 cells.

References

  • Inhibition of phospholipid signalling and proliferation of Swiss 3T3 cells by the wortmannin analogue demethoxyviridin. Cross M.J. et al., Biochim Biophys Acta. 1997, 1362, 29.
  • Effects of phosphatidylinositol-3-kinase inhibitors on degranulation and gene induction in allergically triggered mouse mast cells. Pendl G.G. et al., Int Arch Allergy Immunol. 1997, 112, 392.
  • Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors. Petritsch C. et al., Eur J Biochem. 1995, 230, 431.

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